Upregulation of cyclooxygenase-2 is associated with activation of the alternative nuclear factor kappa B signaling pathway in colonic adenocarcinoma

Cyclooxygenase-2 expression by malignant tumors, including colonic adenocarcinoma, is associated with increased tumor aggression and poor prognosis. Nuclear factor kappa B is a key regulator of cyclooxygenase-2 and is regulated by two pathways, the ‘canonical’ and the ‘alternative’ pathway. The alte...

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Vydáno v:Am J Transl Res
Hlavní autoři: Shi, Guang, Li, Dong, Fu, Jinling, Sun, Yan, Li, Yarong, Qu, Rongfeng, Jin, Xin, Li, Dongfu
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2015
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626422/
https://ncbi.nlm.nih.gov/pubmed/26550460
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