Upregulation of cystathionine beta-synthetase expression by nuclear factor-kappa B activation contributes to visceral hypersensitivity in adult rats with neonatal maternal deprivation

BACKGROUND: Irritable bowel syndrome (IBS) is characterized by chronic visceral hyperalgesia (CVH) that manifested with persistent or recurrent abdominal pain and altered bowel movement. However, the pathogenesis of the CVH remains unknown. The aim of this study was to investigate roles of endogenou...

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Detalhes bibliográficos
Main Authors: Li, Lin, Xie, Ruihua, Hu, Shufen, Wang, Yongmeng, Yu, Tianzhu, Xiao, Ying, Jiang, Xinghong, Gu, Jianguo, Hu, Chuang-Ying, Xu, Guang-Yin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545973/
https://ncbi.nlm.nih.gov/pubmed/23249427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-8-89
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