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The altered autophagy mediated by TFEB in animal and cell models of amyotrophic lateral sclerosis
Autophagy is an intracellular degradation process that clears away aggregated proteins or aged and damaged organelles. Abnormalities in autophagy result in defects in clearance of these misfolded and aggregate proteins, which have been associated with neurodegenerative disorders. A key neuropatholog...
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| Опубликовано в: : | Am J Transl Res |
|---|---|
| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
e-Century Publishing Corporation
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4626419/ https://ncbi.nlm.nih.gov/pubmed/26550457 |
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