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The altered autophagy mediated by TFEB in animal and cell models of amyotrophic lateral sclerosis

Autophagy is an intracellular degradation process that clears away aggregated proteins or aged and damaged organelles. Abnormalities in autophagy result in defects in clearance of these misfolded and aggregate proteins, which have been associated with neurodegenerative disorders. A key neuropatholog...

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Publicat a:Am J Transl Res
Autors principals: Chen, Yanchun, Liu, Huancai, Guan, Yingjun, Wang, Qiaozhen, Zhou, Fenghua, Jie, Linlin, Ju, Jie, Pu, Leidong, Du, Hongmei, Wang, Xin
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626419/
https://ncbi.nlm.nih.gov/pubmed/26550457
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