The altered autophagy mediated by TFEB in animal and cell models of amyotrophic lateral sclerosis

Autophagy is an intracellular degradation process that clears away aggregated proteins or aged and damaged organelles. Abnormalities in autophagy result in defects in clearance of these misfolded and aggregate proteins, which have been associated with neurodegenerative disorders. A key neuropatholog...

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Bibliografske podrobnosti
izdano v:Am J Transl Res
Main Authors: Chen, Yanchun, Liu, Huancai, Guan, Yingjun, Wang, Qiaozhen, Zhou, Fenghua, Jie, Linlin, Ju, Jie, Pu, Leidong, Du, Hongmei, Wang, Xin
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2015
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Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626419/
https://ncbi.nlm.nih.gov/pubmed/26550457
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