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Designing a Study to Evaluate the Benefit of a Biomarker for Selecting Patient Treatment

Biomarkers that predict the efficacy of treatment can potentially improve clinical outcomes and decrease medical costs by allowing treatment to be provided only to those most likely to benefit. We consider the design of a randomized clinical trial in which one objective is to evaluate a treatment se...

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Bibliographic Details
Published in:Stat Med
Main Authors: Janes, Holly, Brown, Marshall D, Pepe, Margaret S
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626364/
https://ncbi.nlm.nih.gov/pubmed/26112650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6564
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