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MDM1 is a microtubule-binding protein that negatively regulates centriole duplication

Mouse double-minute 1 (Mdm1) was originally identified as a gene amplified in transformed mouse cells and more recently as being highly up-regulated during differentiation of multiciliated epithelial cells, a specialized cell type having hundreds of centrioles and motile cilia. Here we show that the...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Van de Mark, Daniel, Kong, Dong, Loncarek, Jadranka, Stearns, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626064/
https://ncbi.nlm.nih.gov/pubmed/26337392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-04-0235
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