HIF-2α-induced chemokines stimulate motility of fibroblast-like synoviocytes and chondrocytes into the cartilage-pannus interface in experimental rheumatoid arthritis mouse models

INTRODUCTION: Pannus formation and resulting cartilage destruction during rheumatoid arthritis (RA) depends on the migration of synoviocytes to cartilage tissue. Here, we focused on the role of hypoxia-inducible factor (HIF)-2α-induced chemokines by chondrocytes in the regulation of fibroblast-like...

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Vydáno v:Arthritis Res Ther
Hlavní autoři: Huh, Yun Hyun, Lee, Gyuseok, Lee, Keun-Bae, Koh, Jeong-Tae, Chun, Jang-Soo, Ryu, Je-Hwang
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625947/
https://ncbi.nlm.nih.gov/pubmed/26510617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0816-x
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