A Podocyte-Based Automated Screening Assay Identifies Protective Small Molecules

Podocyte injury and loss mark an early step in the pathogenesis of various glomerular diseases, making these cells excellent targets for therapeutics. However, cell–based high–throughput screening assays for the rational development of podocyte-directed therapeutics are currently lacking. Here, we d...

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Detalles Bibliográficos
Publicado en:J Am Soc Nephrol
Autores principales: Lee, Ha Won, Khan, Samia Q., Faridi, Mohd Hafeez, Wei, Changli, Tardi, Nicholas J., Altintas, Mehmet M., Elshabrawy, Hatem A., Mangos, Steve, Quick, Kevin L., Sever, Sanja, Reiser, Jochen, Gupta, Vineet
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Nephrology 2015
Materias:
Basic Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625676/
https://ncbi.nlm.nih.gov/pubmed/25858967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014090859
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