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Caveolin-1 Deficiency Inhibits the Basolateral K(+) Channels in the Distal Convoluted Tubule and Impairs Renal K(+) and Mg(2+) Transport

Kcnj10 encodes the inwardly rectifying K(+) channel Kir4.1 in the basolateral membrane of the distal convoluted tubule (DCT) and is activated by c-Src. However, the regulation and function of this K(+) channel are incompletely characterized. Here, patch-clamp experiments in Kcnj10-transfected HEK293...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Wang, Lijun, Zhang, Chengbiao, Su, Xiaotong, Lin, Dao-Hong, Wang, Wenhui
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625665/
https://ncbi.nlm.nih.gov/pubmed/25848073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014070658
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