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Distal convoluted tubule Cl(−) concentration is modulated via K(+) channels and transporters
Cl(−)-sensitive with-no-lysine kinase (WNK) plays a key role in regulating the thiazide-sensitive Na(+)-Cl(−) cotransporter (NCC) in the distal convoluted tubule (DCT). Cl(−) enters DCT cells through NCC and leaves the cell across the basolateral membrane via the Cl(−) channel ClC-K2 or K(+)-Cl(−) c...
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| Veröffentlicht in: | Am J Physiol Renal Physiol |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7509289/ https://ncbi.nlm.nih.gov/pubmed/32715757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00284.2020 |
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