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5-Azacytidine modulates interferon regulatory factor 1 in macrophages to exert a cardioprotective effect
Macrophages are actively involved in inflammatory responses during the progression of cardiac injury, including myocardial infarction (MI). A previous study showed that 5-azacytidine (5AZ), a DNA methylation inhibitor, can ameliorate cardiac injury by shifting macrophages toward an anti-inflammatory...
שמור ב:
| הוצא לאור ב: | Sci Rep |
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| Main Authors: | , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4625165/ https://ncbi.nlm.nih.gov/pubmed/26510961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15768 |
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