5-Azacytidine modulates interferon regulatory factor 1 in macrophages to exert a cardioprotective effect

Macrophages are actively involved in inflammatory responses during the progression of cardiac injury, including myocardial infarction (MI). A previous study showed that 5-azacytidine (5AZ), a DNA methylation inhibitor, can ameliorate cardiac injury by shifting macrophages toward an anti-inflammatory...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Jeong, Hye-yun, Kang, Wan Seok, Hong, Moon Hwa, Jeong, Hae Chang, Shin, Myun-Geun, Jeong, Myung Ho, Kim, Yong Sook, Ahn, Youngkeun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625165/
https://ncbi.nlm.nih.gov/pubmed/26510961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15768
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg