Secreted Ephrin Receptor A7 Promotes Somatic Cell Reprogramming by Inducing ERK Activity Reduction

The role of secreted molecules in cellular reprogramming has been poorly understood. Here we identify a truncated form of ephrin receptor A7 (EPHA7) as a key regulator of reprogramming. Truncated EPHA7 is prominently upregulated and secreted during reprogramming. EPHA7 expression is directly regulat...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Lee, Joonseong, Nakajima-Koyama, May, Sone, Masamitsu, Koga, Makito, Ebisuya, Miki, Yamamoto, Takuya, Nishida, Eisuke
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625027/
https://ncbi.nlm.nih.gov/pubmed/26441306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.09.001
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