Mucosal Immunogenicity of Genetically Modified Lactobacillus acidophilus Expressing an HIV-1 Epitope within the Surface Layer Protein

Surface layer proteins of probiotic lactobacilli are theoretically efficient epitope-displaying scaffolds for oral vaccine delivery due to their high expression levels and surface localization. In this study, we constructed genetically modified Lactobacillus acidophilus strains expressing the membra...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Kajikawa, Akinobu, Zhang, Lin, LaVoy, Alora, Bumgardner, Sara, Klaenhammer, Todd R., Dean, Gregg A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624987/
https://ncbi.nlm.nih.gov/pubmed/26509697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141713
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