PTPN13 and β-Catenin Regulate the Quiescence of Hematopoietic Stem Cells and Their Interaction with the Bone Marrow Niche

The regulation of hematopoietic stem cells (HSCs) depends on the integration of the multiple signals received from the bone marrow niche. We show the relevance of the protein tyrosine phosphatase PTPN13 and β-catenin as intracellular signaling molecules to control HSCs adhesiveness, cell cycling, an...

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Pubblicato in:Stem Cell Reports
Autori principali: López-Ruano, Guillermo, Prieto-Bermejo, Rodrigo, Ramos, Teresa L., San-Segundo, Laura, Sánchez-Abarca, Luis Ignacio, Sánchez-Guijo, Fermín, Pérez-Simón, José Antonio, Sánchez-Yagüe, Jesús, Llanillo, Marcial, Hernández-Hernández, Ángel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624939/
https://ncbi.nlm.nih.gov/pubmed/26344907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.08.003
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