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Inter occasion variability in individual optimal design
Inter occasion variability (IOV) is of importance to consider in the development of a design where individual pharmacokinetic or pharmacodynamic parameters are of interest. IOV may adversely affect the precision of maximum a posteriori (MAP) estimated individual parameters, yet the influence of incl...
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| Publicado no: | J Pharmacokinet Pharmacodyn |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4624834/ https://ncbi.nlm.nih.gov/pubmed/26452548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-015-9449-6 |
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