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A highly coupled network of tertiary interactions in the SAM-I riboswitch and their role in regulatory tuning

RNA folding in vivo is significantly influenced by transcription, which is not necessarily recapitulated by Mg(2+)-induced folding of the corresponding full length RNA in vitro. Riboswitches that regulate gene expression at the transcriptional level are an ideal system for investigating this aspect...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Wostenberg, Christopher, Ceres, Pablo, Polaski, Jacob T., Batey, Robert T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624507/
https://ncbi.nlm.nih.gov/pubmed/26343759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.07.027
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