Handling Permutation in Sequence Comparison: Genome-Wide Enhancer Prediction in Vertebrates by a Novel Non-Linear Alignment Scoring Principle

Enhancers have been described to evolve by permutation without changing function. This has posed the problem of how to predict enhancer elements that are hidden from alignment-based approaches due to the loss of co-linearity. Alignment-free algorithms have been proposed as one possible solution. How...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Dolle, Dirk, Mateo, Juan L., Eichenlaub, Michael P., Sinn, Rebecca, Reinhardt, Robert, Höckendorf, Burkhard, Inoue, Daigo, Centanin, Lazaro, Ettwiller, Laurence, Wittbrodt, Joachim
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624239/
https://ncbi.nlm.nih.gov/pubmed/26505748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141487
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