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DNA-Binding Kinetics Determines the Mechanism of Noise-Induced Switching in Gene Networks

Gene regulatory networks are multistable dynamical systems in which attractor states represent cell phenotypes. Spontaneous, noise-induced transitions between these states are thought to underlie critical cellular processes, including cell developmental fate decisions, phenotypic plasticity in fluct...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Tse, Margaret J., Chu, Brian K., Roy, Mahua, Read, Elizabeth L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624158/
https://ncbi.nlm.nih.gov/pubmed/26488666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.08.035
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