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α-Tocopherol Is Well Designed to Protect Polyunsaturated Phospholipids: MD Simulations

The presumptive function for alpha-tocopherol (αtoc) in membranes is to protect polyunsaturated lipids against oxidation. Although the chemistry of the process is well established, the role played by molecular structure that we address here with atomistic molecular-dynamics simulations remains contr...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Leng, Xiaoling, Kinnun, Jacob J., Marquardt, Drew, Ghefli, Mikel, Kučerka, Norbert, Katsaras, John, Atkinson, Jeffrey, Harroun, Thad A., Feller, Scott E., Wassall, Stephen R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624157/
https://ncbi.nlm.nih.gov/pubmed/26488652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.08.032
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