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Computation of pH-Dependent Binding Free Energies

Protein-ligand binding accompanies changes in the surrounding electrostatic environments of the two binding partners and may lead to changes in protonation upon binding. In cases where the complex formation results in a net transfer of protons, the binding process is pH-dependent. However, conventio...

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Detalles Bibliográficos
Publicado en:Biopolymers
Main Authors: Kim, M. Olivia, McCammon, J. Andrew
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623928/
https://ncbi.nlm.nih.gov/pubmed/26202905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.22702
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