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Nanoparticle Modulation of the Tumor Microenvironment Enhances Therapeutic Efficacy of Cisplatin

The tumor microenvironment (TME) serves as an innate resistance niche for chemotherapy assault and a physiological barrier against therapeutic nanoparticles (NP) penetration. Previous studies have indicated that therapeutic NP can distribute to and deplete tumor associated fibroblasts (TAF) for impr...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Miao, Lei, Wang, Yuhua, Xiong, Yang, Lin, C. Michael, Chen, Naihan, Zhang, Lu, Kim, William Y., Huang, Leaf
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623876/
https://ncbi.nlm.nih.gov/pubmed/26285063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.08.027
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