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Unmodified Drug Used as a Material to Construct Nanoparticles: Delivery of Cisplatin for Enhanced Anti-Cancer Therapy

The poor solubility of cisplatin (CDDP) often presents a major obstacle in the formulation of CDDP in nanoparticles (NPs) by traditional methods. We have developed a novel method for synthesizing CDDP NPs taking advantage of its poor solubility. By mixing two reverse microemulsions containing KCl an...

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Detalhes bibliográficos
Main Authors: Guo, Shutao, Miao, Lei, Wang, Yuhua, Huang, Leaf
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946998/
https://ncbi.nlm.nih.gov/pubmed/24280262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2013.11.019
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