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Production of bispecific antibodies in “knobs-into-holes” using a cell-free expression system

Bispecific antibodies have emerged in recent years as a promising field of research for therapies in oncology, inflammable diseases, and infectious diseases. Their capability of dual target recognition allows for novel therapeutic hypothesis to be tested, where traditional mono-specific antibodies w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:MAbs
Hauptverfasser: Xu, Yiren, Lee, John, Tran, Cuong, Heibeck, Tyler H, Wang, Willie D, Yang, Junhao, Stafford, Ryan L, Steiner, Alexander R, Sato, Aaron K, Hallam, Trevor J, Yin, Gang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623329/
https://ncbi.nlm.nih.gov/pubmed/25427258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19420862.2015.989013
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