Preclinical and early clinical development of GNbAC1, a humanized IgG4 monoclonal antibody targeting endogenous retroviral MSRV-Env protein

Monoclonal antibodies (mAbs) play an increasing important role in the therapeutic armamentarium against multiple sclerosis (MS), an inflammatory and degenerative disorder of the central nervous system. Most of the mAbs currently developed for MS are immunomodulators blocking the inflammatory immune...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Curtin, François, Perron, Hervé, Kromminga, Arno, Porchet, Hervé, Lang, Alois B
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623301/
https://ncbi.nlm.nih.gov/pubmed/25427053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19420862.2014.985021
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