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Inhibition of plasminogen activator inhibitor-1 is a potential therapeutic strategy in ovarian cancer

Plasminogen activator inhibitor (PAI)-1 is predictive of poor outcome in several types of cancer. The present study investigated the biological role for PAI-1 in ovarian cancer and potential of targeted pharmacotherapeutics. In patients with ovarian cancer, PAI-1 mRNA expression in tumor tissues was...

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Détails bibliographiques
Publié dans:Cancer Biol Ther
Auteurs principaux: Mashiko, Satsuki, Kitatani, Kazuyuki, Toyoshima, Masafumi, Ichimura, Atsuhiko, Dan, Takashi, Usui, Toshinori, Ishibashi, Masumi, Shigeta, Shogo, Nagase, Satoru, Miyata, Toshio, Yaegashi, Nobuo
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623014/
https://ncbi.nlm.nih.gov/pubmed/25587663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2014.1001271
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