Q-RRBS: a quantitative reduced representation bisulfite sequencing method for single-cell methylome analyses

Reduced representation bisulfite sequencing (RRBS) is a powerful method of DNA methylome profiling that can be applied to single cells. However, no previous report has described how PCR-based duplication-induced artifacts affect the accuracy of this method when measuring DNA methylation levels. For...

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Bibliografiske detaljer
Udgivet i:Epigenetics
Main Authors: Wang, Kangli, Li, Xianfeng, Dong, Shanshan, Liang, Jialong, Mao, Fengbiao, Zeng, Cheng, Wu, Honghu, Wu, Jinyu, Cai, Wanshi, Sun, Zhong Sheng
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Brief Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622980/
https://ncbi.nlm.nih.gov/pubmed/26213102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2015.1075690
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