Dysregulated Class I histone deacetylases are indicators of poor prognosis in multiple myeloma

Histone deacetylases (HDAC) control gene expression through their ability to acetylate proteins, thereby influencing a diverse range of cellular functions. Class I HDAC (HDAC1–3 and 8) and HDAC6 are predominantly upregulated in malignancies and their altered expression in some cancers has a signific...

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Detalles Bibliográficos
Publicado en:Epigenetics
Autores principales: Mithraprabhu, Sridurga, Kalff, Anna, Chow, Annie, Khong, Tiffany, Spencer, Andrew
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2014
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622977/
https://ncbi.nlm.nih.gov/pubmed/25482492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15592294.2014.983367
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