Time-Resolved Imaging Reveals Heterogeneous Landscapes of Nanomolar Ca(2+) in Neurons and Astroglia

Maintaining low intracellular calcium is essential to the functioning of brain cells, yet the phenomenology and mechanisms involved remain an enigma. We have advanced a two-photon excitation time-resolved imaging technique, which exploits high sensitivity of the OGB-1 fluorescence lifetime to nanomo...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Zheng, Kaiyu, Bard, Lucie, Reynolds, James P., King, Claire, Jensen, Thomas P., Gourine, Alexander V., Rusakov, Dmitri A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2015
Assuntos:
NeuroResource
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622934/
https://ncbi.nlm.nih.gov/pubmed/26494277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2015.09.043
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