Wird geladen...

Vertical Targeting of AKT and mTOR as Well as Dual Targeting of AKT and MEK Signaling Is Synergistic in Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is the sixth most common cancer, and the third most common cause of cancer related death worldwide. The multi-kinase inhibitor Sorafenib represents the only systemic treatment option until today, and results from clinical trials with allosteric mTOR inhibitors were sob...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Cancer
Hauptverfasser: Ewald, Florian, Nörz, Dominik, Grottke, Astrid, Bach, Johanna, Herzberger, Christiane, Hofmann, Bianca T., Nashan, Björn, Jücker, Manfred
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622849/
https://ncbi.nlm.nih.gov/pubmed/26535060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.12452
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!