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Consistency of quality attributes for the glycosylated monoclonal antibody Humira® (adalimumab)

Humira® (adalimumab) is a recombinant human IgG1 monoclonal antibody (mAb) glycoprotein consisting of 1330 amino acids that is specific for human tumor necrosis factor (TNF). The biological activity and clinical profile of mAb therapeutics, including adalimumab, is influenced by their protein struct...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:MAbs
Hauptverfasser: Tebbey, Paul W, Varga, Amy, Naill, Michael, Clewell, Jerry, Venema, Jaap
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622832/
https://ncbi.nlm.nih.gov/pubmed/26230301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1073429
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