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Quality by Design–Based Assessment for Analytical Similarity of Adalimumab Biosimilar HLX03 to Humira®

Quality by design (QbD) is an efficient but challenging approach for the development of biosimilar due to the complex relationship among process, quality, and efficacy. Here, the analytical similarity of adalimumab biosimilar HLX03 to Humira® was successfully established following a QbD quality stud...

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Bibliografiske detaljer
Udgivet i:AAPS J
Main Authors: Zhang, Erhui, Xie, Liqi, Qin, Peilan, Lu, Lihong, Xu, Yanpeng, Gao, Wenyuan, Wang, Linlin, Xie, Michael Hongwei, Jiang, Weidong, Liu, Scott
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7210234/
https://ncbi.nlm.nih.gov/pubmed/32385732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-020-00454-z
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