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Epigenetic analysis of sporadic and Lynch-associated ovarian cancers reveals histology-specific patterns of DNA methylation

Diagnosis and treatment of epithelial ovarian cancer is challenging due to the poor understanding of the pathogenesis of the disease. Our aim was to investigate epigenetic mechanisms in ovarian tumorigenesis and, especially, whether tumors with different histological subtypes or hereditary backgroun...

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Bibliografske podrobnosti
izdano v:Epigenetics
Main Authors: Niskakoski, Anni, Kaur, Sippy, Staff, Synnöve, Renkonen-Sinisalo, Laura, Lassus, Heini, Järvinen, Heikki J, Mecklin, Jukka-Pekka, Bützow, Ralf, Peltomäki, Päivi
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622692/
https://ncbi.nlm.nih.gov/pubmed/25625843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15592294.2014.983374
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