Inhibition of autophagy overcomes glucocorticoid resistance in lymphoid malignant cells

Glucocorticoid (GC) resistance remains a major obstacle to successful treatment of lymphoid malignancies. Till now, the precise mechanism of GC resistance remains unclear. In the present study, dexamethasone (Dex) inhibited cell proliferation, arrested cell cycle in G0/G1-phase, and induced apoptosi...

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Dades bibliogràfiques
Publicat a:Cancer Biol Ther
Autors principals: Jiang, Lei, Xu, Lingzhi, Xie, Jiajun, Li, Sisi, Guan, Yanchun, Zhang, Yan, Hou, Zhijie, Guo, Tao, Shu, Xin, Wang, Chang, Fan, Wenjun, Si, Yang, Yang, Ya, Kang, Zhijie, Fang, Meiyun, Liu, Quentin
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622576/
https://ncbi.nlm.nih.gov/pubmed/25778879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1016658
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