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A general strategy for generating intact, full-length IgG antibodies that penetrate into the cytosol of living cells
Full-length IgG antibodies cannot cross cell membranes of living cells; this limits their use for direct targeting of cytosolic proteins. Here, we describe a general strategy for the generation of intact, full-length IgG antibodies, herein called cytotransmabs, which internalize into living cells an...
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| Publicado no: | MAbs |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4622575/ https://ncbi.nlm.nih.gov/pubmed/25484049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.36389 |
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