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A peptide nucleic acid targeting nuclear RAD51 sensitizes multiple myeloma cells to melphalan treatment
RAD51-mediated recombinational repair is elevated in multiple myeloma (MM) and predicts poor prognosis. RAD51 has been targeted to selectively sensitize and/or kill tumor cells. Here, we employed a peptide nucleic acid (PNA) to inhibit RAD51 expression in MM cells. We constructed a PNA complementary...
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| Publicado no: | Cancer Biol Ther |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4622566/ https://ncbi.nlm.nih.gov/pubmed/25996477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1040951 |
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