Generation of CD8(+) T cells expressing two additional T-cell receptors (TETARs) for personalised melanoma therapy

Adoptive T-cell therapy of cancer often fails due to the tumor cells' immune escape mechanisms, like antigen loss or down-regulation. To anticipate immune escape by loss of a single antigen, it would be advantageous to equip T cells with multiple specificities. To study the possible interferenc...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Höfflin, Sandra, Prommersberger, Sabrina, Uslu, Ugur, Schuler, Gerold, Schmidt, Christopher W, Lennerz, Volker, Dörrie, Jan, Schaft, Niels
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622550/
https://ncbi.nlm.nih.gov/pubmed/26178065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1070981
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados