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Beyond the histone tale: HP1α deregulation in breast cancer epigenetics
Heterochromatin protein 1α (HP1α) encoded from the CBX5-gene is an evolutionary conserved protein that binds histone H3 di- or tri-methylated at position lysine 9 (H3K9me2/3), a hallmark for heterochromatin, and has an essential role in forming higher order chromatin structures. HP1α has diverse fun...
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| Vydáno v: | Cancer Biol Ther |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4622548/ https://ncbi.nlm.nih.gov/pubmed/25588111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2014.1001277 |
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