Epigenetic silencing of neurofilament genes promotes an aggressive phenotype in breast cancer

Neurofilament heavy polypeptide (NEFH) has recently been identified as a candidate DNA hypermethylated gene within the functional breast cancer hypermethylome. NEFH exists in a complex with neurofilament medium polypeptide (NEFM) and neurofilament light polypeptide (NEFL) to form neurofilaments, whi...

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Pubblicato in:Epigenetics
Autori principali: Calmon, Marilia Freitas, Jeschke, Jana, Zhang, Wei, Dhir, Mashaal, Siebenkäs, Cornelia, Herrera, Alexander, Tsai, Hsing-Chen, O'Hagan, Heather M, Pappou, Emmanouil P, Hooker, Craig M, Fu, Tao, Schuebel, Kornel E, Gabrielson, Edward, Rahal, Paula, Herman, James G, Baylin, Stephen B, Ahuja, Nita
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2015
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622480/
https://ncbi.nlm.nih.gov/pubmed/25985363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2015.1050173
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