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Inhibiting DNA methylation activates cancer testis antigens and expression of the antigen processing and presentation machinery in colon and ovarian cancer cells

Innovative therapies for solid tumors are urgently needed. Recently, therapies that harness the host immune system to fight cancer cells have successfully treated a subset of patients with solid tumors. These responses have been strong and durable but observed in subsets of patients. Work from our g...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Siebenkäs, Cornelia, Chiappinelli, Katherine B., Guzzetta, Angela A., Sharma, Anup, Jeschke, Jana, Vatapalli, Rajita, Baylin, Stephen B., Ahuja, Nita
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473589/
https://ncbi.nlm.nih.gov/pubmed/28622390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179501
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