Targeting CD64 mediates elimination of M1 but not M2 macrophages in vitro and in cutaneous inflammation in mice and patient biopsies

Macrophages are key players in controlling the immune response that can adapt to microenvironmental signals. This results in distinct polarization states (classical M1 or alternative M2), that play a differential role in immune regulation. In general, the M1 contribute to onset of inflammation, wher...

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Bibliographische Detailangaben
Veröffentlicht in:MAbs
Hauptverfasser: Hristodorov, Dmitrij, Mladenov, Radoslav, von Felbert, Verena, Huhn, Michael, Fischer, Rainer, Barth, Stefan, Thepen, Theo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2015
Schlagworte:
Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622427/
https://ncbi.nlm.nih.gov/pubmed/26218624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1066950
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