Targeting CD64 mediates elimination of M1 but not M2 macrophages in vitro and in cutaneous inflammation in mice and patient biopsies

Macrophages are key players in controlling the immune response that can adapt to microenvironmental signals. This results in distinct polarization states (classical M1 or alternative M2), that play a differential role in immune regulation. In general, the M1 contribute to onset of inflammation, wher...

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Bibliografiska uppgifter
I publikationen:MAbs
Huvudupphovsmän: Hristodorov, Dmitrij, Mladenov, Radoslav, von Felbert, Verena, Huhn, Michael, Fischer, Rainer, Barth, Stefan, Thepen, Theo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2015
Ämnen:
Report
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622427/
https://ncbi.nlm.nih.gov/pubmed/26218624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1066950
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