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rs712 polymorphism within let-7 microRNA-binding site might be involved in the initiation and progression of colorectal cancer in Chinese population

rs712 within 3′-untranslated region of KRAS can affect the specific binding between the mRNA and its targeted microRNAs, leading to the activation of KRAS oncogene. However, the possible association between the locus and susceptibility to colorectal cancer (CRC) remains unclear. We investigated geno...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Jiang, Qiang-Hua, Peng, Hong-Xin, Zhang, Yi, Tian, Peng, Xi, Zu-Lian, Chen, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622418/
https://ncbi.nlm.nih.gov/pubmed/26543374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S89746
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