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rs712 polymorphism within let-7 microRNA-binding site might be involved in the initiation and progression of colorectal cancer in Chinese population

rs712 within 3′-untranslated region of KRAS can affect the specific binding between the mRNA and its targeted microRNAs, leading to the activation of KRAS oncogene. However, the possible association between the locus and susceptibility to colorectal cancer (CRC) remains unclear. We investigated geno...

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Bibliografische gegevens
Gepubliceerd in:Onco Targets Ther
Hoofdauteurs: Jiang, Qiang-Hua, Peng, Hong-Xin, Zhang, Yi, Tian, Peng, Xi, Zu-Lian, Chen, Hao
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Dove Medical Press 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622418/
https://ncbi.nlm.nih.gov/pubmed/26543374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S89746
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