Recombinant renewable polyclonal antibodies

Only a small fraction of the antibodies in a traditional polyclonal antibody mixture recognize the target of interest, frequently resulting in undesirable polyreactivity. Here, we show that high-quality recombinant polyclonals, in which hundreds of different antibodies are all directed toward a targ...

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Pubblicato in:MAbs
Autori principali: Ferrara, Fortunato, D’Angelo, Sara, Gaiotto, Tiziano, Naranjo, Leslie, Tian, Hongzhao, Gräslund, Susanne, Dobrovetsky, Elena, Hraber, Peter, Lund-Johansen, Fridtjof, Saragozza, Silvia, Sblattero, Daniele, Kiss, Csaba, Bradbury, Andrew RM
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2014
Soggetti:
Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622072/
https://ncbi.nlm.nih.gov/pubmed/25530082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19420862.2015.989047
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