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Many Routes to an Antibody Heavy-Chain CDR3: Necessary, Yet Insufficient, for Specific Binding
Because of its great potential for diversity, the immunoglobulin heavy-chain complementarity-determining region 3 (HCDR3) is taken as an antibody molecule’s most important component in conferring binding activity and specificity. For this reason, HCDR3s have been used as unique identifiers to invest...
Shranjeno v:
izdano v: | Front Immunol |
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Main Authors: | , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Frontiers Media S.A.
2018
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5852061/ https://ncbi.nlm.nih.gov/pubmed/29568296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00395 |
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