C-type lectin-like molecule-1 (CLL1)-targeted TRAIL augments the tumoricidal activity of granulocytes and potentiates therapeutic antibody-dependent cell-mediated cytotoxicity

The therapeutic effect of anti-cancer monoclonal antibodies stems from their capacity to opsonize targeted cancer cells with subsequent phagocytic removal, induction of antibody-dependent cell-mediated cytotoxicity (ADCC) or induction of complement-mediated cytotoxicity (CDC). The major immune effec...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Wiersma, Valerie R, de Bruyn, Marco, Shi, Ce, Gooden, Marloes JM, Wouters, Maartje CA, Samplonius, Douwe F, Hendriks, Djoke, Nijman, Hans W, Wei, Yunwei, Zhou, Jin, Helfrich, Wijnand, Bremer, Edwin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622055/
https://ncbi.nlm.nih.gov/pubmed/25760768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1007811
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