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Epigenetic switches in clag3 genes mediate blasticidin S resistance in malaria parasites

Malaria parasites induce changes in the permeability of the infected erythrocyte membrane to numerous solutes, including toxic compounds. In Plasmodium falciparum, this is mainly mediated by PSAC, a broad-selectivity channel that requires the product of parasite clag3 genes for its activity. The two...

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Détails bibliographiques
Publié dans:Cell Microbiol
Auteurs principaux: Mira-Martínez, Sofía, Rovira-Graells, Núria, Crowley, Valerie M., Altenhofen, Lindsey M., Llinás, Manuel, Cortés, Alfred
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621952/
https://ncbi.nlm.nih.gov/pubmed/23819786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12162
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