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Epigenetic switches in clag3 genes mediate blasticidin S resistance in malaria parasites

Malaria parasites induce changes in the permeability of the infected erythrocyte membrane to numerous solutes, including toxic compounds. In Plasmodium falciparum, this is mainly mediated by PSAC, a broad-selectivity channel that requires the product of parasite clag3 genes for its activity. The two...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Microbiol
Hauptverfasser: Mira-Martínez, Sofía, Rovira-Graells, Núria, Crowley, Valerie M., Altenhofen, Lindsey M., Llinás, Manuel, Cortés, Alfred
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621952/
https://ncbi.nlm.nih.gov/pubmed/23819786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12162
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