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S-thanatin functionalized liposome potentially targeting on Klebsiella pneumoniae and its application in sepsis mouse model

S-thanatin (Ts) was a short antimicrobial peptide with selective antibacterial activity. In this study, we aimed to design a drug carrier with specific bacterial targeting potential. The positively charged Ts was modified onto the liposome surface by linking Ts to the constituent lipids via a PEG li...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Fan, Xiaobo, Fan, Juxiang, Wang, Xiyong, Wu, Pengpeng, Wu, Guoqiu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621865/
https://ncbi.nlm.nih.gov/pubmed/26578959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00249
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