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A Novel Pentapeptide Targeting Integrin β3-Subunit Inhibits Platelet Aggregation and Its Application in Rat for Thrombosis Prevention

Background: Antiplatelet therapy plays a pivotal role in the prevention and treatment of thrombotic diseases. We reported the screening of P1C as a novel integrin-binding peptide from the C-terminal of connective tissue growth factor. Primary study indicated that P1C has potential against platelet a...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Qu, Qingrong, Liu, Yamin, Yan, Xuejiao, Fan, Xiaobo, Liu, Naifeng, Wu, Guoqiu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782163/
https://ncbi.nlm.nih.gov/pubmed/27014063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00049
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